DAPARIN 10 Tablet 10's

INTRODUCTION ABOUT DAPARIN 10 TABLET

DAPARIN 10 TABLET is used to manage type II diabetes mellitus when diet and exercise does not result in adequate control on blood glucose levels. It is also used in the management of heart failure and chronic kidney disease (reduced kidney function). It contains Dapagliflozin which belongs to the group of medicines called Antidiabetic agents.

During therapy with DAPARIN 10 TABLET, your doctor might regularly monitor blood sugar levels and kidney functions to avoid the risk of unwanted side effects. Before taking the medicine, inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have type I diabetes, severe low blood pressure, severe dehydration or conditions which can cause dehydration (such as nausea, vomiting, fever, serious illness or any surgery).

The most common side effects are back pain, passing more urine, constipation, dizziness and rash. Consult your physician if any of these side effect worsens.

USES OF DAPARIN 10 TABLET

It is used to manage:

• Type II diabetes mellitus  
• Heart failure
• Chronic kidney disease

HOW DAPARIN 10 TABLET WORKS

DAPARIN 10 TABLET contains Dapagliflozin which works by blocking the action of a protein called SGLT-2 in the kidneys. This action manages the reabsorption of glucose and sodium ions in the kidneys. As a result, it excretes excess glucose and from the body in the form urine leading to decrease in blood sugar levels. It also protects kidney function and manages it from further damage. Additionally, it reduces the strain on the heart and helps it to pump blood more efficiently with less pressure.

DIRECTIONS FOR USE

• Take DAPARIN 10 TABLET as advised by your physician
• Swallow the medicine with a glass of water. Do not crush or chew the medicine. It can be taken with or without meals
• Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition
• Do not stop taking DAPARIN 10 TABLET unless your doctor advice you to stop

SIDE EFFECTS OF DAPARIN 10 TABLET

Common side effects of DAPARIN 10 TABLET:

• fungal infections of genital (thrush) causing itching, irritation, unusual discharge, odor
• back pain
• passing more urine, increased urine frequency
• dizziness
• skin rash
• dehydration, thirst
• constipation
• dry mouth

Stop taking DAPARIN 10 TABLET and contact your doctor immediately if you experience any of the following side effects such as:

• signs of allergic reaction (skin rash, itching, swelling of the face, tongue or throat, causing difficulty in breathing and swallowing)
• signs of diabetic ketoacidosis (nausea or vomiting, stomach pain, excessive thirst, fast and deep breathing, confusion, unusual sleepiness or tiredness, a sweet smell to breath, a sweet or metallic taste in the mouth or a different odor to urine or sweat, and rapid weight loss)
• pain, swelling, redness or tenderness of the genitals or the areas between the genitals and the anus accompanied with high fever or a feeling generally unwell (sign of necrotizing fasciitis of the perineum)
• signs of urinary tract infection (such as fever and/or chills, burning sensation while passing urine, pain in the back or side)
• bloody urine
• signs of low blood sugar levels (shaking, sweating, anxiety, hunger, fast heartbeat, headache, change in vision, mood swings, confusion)

WARNING & PRECAUTIONS

PREGNANCY

Consult your doctor

There are limited for the use of DAPARIN 10 TABLET in pregnant women Therefore, the use of this medicine is not recommended during the second and third trimesters of pregnancy.

BREASTFEEDING

Consult your doctor

It is unknown whether DAPARIN 10 TABLET and/or its metabolites are excreted in human milk. Consult your doctor before taking the medicine.

DRIVING AND USING MACHINES

Use with Caution

DAPARIN 10 TABLET does not affect your ability to drive or operate any heavy tools or machines. However, if it is combined with other antidiabetic medicines, it may cause dizziness, shakiness, or vision changes. Therefore, do not drive or handle any heavy tools if your ability is affected by the medicine.

ALCOHOL

Consult your doctor

Avoid consumption of alcohol while taking DAPARIN 10 TABLET as it may increase the risk of unwanted side effects.

KIDNEY

Use with Caution

DAPARIN 10 TABLET should be used with caution in patients with kidney problems.  

LIVER

Use with Caution

DAPARIN 10 TABLET should be used with caution in patients with liver problems.

ALLERGY

Contraindicated

Do not take DAPARIN 10 TABLET if you are allergic to Dapagliflozin or any other ingredients of this medicine.

USE IN PEDIATRICS

Consult your doctor

There is no data available in children below 10 years of age. Consult your doctor for advice.

USE IN GERIATRICS

Use with Caution

DAPARIN 10 TABLET should be used with caution in elderly patients (aged 65 years or above).

INTERACTIONS

A. Drug-Drug interactions:

Before taking the medicine, inform your doctor if you are taking any of the following medicines such as:

• diuretics (Ex. furosemide, hydrochlorothiazide)
• Antidiabetics (Ex. insulin or glimepiride, gliclazide)

Overdosage:

If you or anyone else accidentally take too much of DAPARIN 10 TABLET, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS

FAQs ABOUT DAPARIN 10 TABLET

Q: What is DAPARIN 10 TABLET used for?

A: DAPARIN 10 TABLET is used to manage type II diabetes mellitus in adults and in children (aged 10 years or older) when diet and exercise does not result in adequate control on blood glucose levels. It can also be used to manage heart failure and chronic kidney disease (reduced kidney function) in adults.

Q: Is DAPARIN 10 TABLET safe to use in children?

A: There are limited for the use of DAPARIN 10 TABLET in pregnant women Therefore, the use of this medicine is not recommended during the second and third trimesters of pregnancy.

Q: Can the use of DAPARIN 10 TABLET cause weight loss?

A: DAPARIN 10 TABLET may cause weight loss in some individuals. It is because of excessive loss of fluid from the body in the form of urine. However, consult your doctor if this side effect troubles you. 

Q: Can DAPARIN 10 TABLET affects pregnancy?

A: There are limited for the use of DAPARIN 10 TABLET in pregnant women Therefore, the use of this medicine is not recommended during the second and third trimesters of pregnancy.

Q: Can DAPARIN 10 TABLET cause urinary tract infection?

A: Yes, taking DAPARIN 10 TABLET may cause urinary tract infections in few peoples. Not every individual gets the side effect, so it is always better to practice good hygiene. Contact your doctor for advice.

Q: How does DAPARIN 10 TABLET work?

A: DAPARIN 10 TABLET is a SGLT-2 inhibitor. It works by blocking the action of a protein called SGLT-2 in the kidneys. This action manages the reabsorption of glucose and sodium ions in the kidneys. As a result, it excretes excess glucose and from the body in the form urine leading to decrease in blood sugar levels. It also protects kidney function and manages it from further damage. Additionally, it reduces the strain on the heart and helps it to pump blood more efficiently with less pressure.

Q: How and when to take DAPARIN 10 TABLET?

A: Take DAPARIN 10 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. It can be taken with or without meals.

Q: How long should I take DAPARIN 10 TABLET?

A: You need to take DAPARIN 10 TABLET as long as your doctor prescribes you the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.

Q: What to do if I forgot to take a dose of DAPARIN 10 TABLET?

A: If you forgot to take a dose of DAPARIN 10 TABLET, take it as soon as you remember. However, if it is time for the next dose of DAPARIN 10 TABLET, skip the missed dose and take the next one regularly.

Q: What are the most common side effects of taking DAPARIN 10 TABLET?

A: The most common side effects of taking DAPARIN 10 TABLET are genital infections, back pain, passing more urine, constipation, dizziness and rash. Contact your physician if any of these side effect worsens.

Q: Will taking a higher dose of DAPARIN 10 TABLET be more effective?

A: No, taking a higher dose of DAPARIN 10 TABLET will not be effective rather it can lead to toxicity. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.   

Q: What precautions do I need to follow while taking DAPARIN 10 TABLET?

A: Before taking DAPARIN 10 TABLET inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have severe low blood pressure or are severely dehydrated due to excessive vomiting or diarrhea. Along with the therapy, follow the diet and lifestyle changes advised by your doctor to achieve better results.

Q: Can I take DAPARIN 10 TABLET with metformin?

A: Studies have shown that the combination of DAPARIN 10 TABLET with metformin may effectively control blood sugar levels. However, the combination should be used only under careful medical supervision.

Q: Can DAPARIN 10 TABLET be taken with insulin?

A: Co-administration of DAPARIN 10 TABLET with insulin is considered risky as they increase the chance of hypoglycemia (decreased blood sugar levels). Therefore, consult your doctor before taking it.

Q: Can DAPARIN 10 TABLET cause constipation?

A: Yes. Constipation is a common side effect of taking DAPARIN 10 TABLET. Eat plenty of fiber rich foods such as fresh fruits, vegetables, cereals as well as drink plenty of water and exercise more regularly while taking this medicine. Contact your doctor if this side effect bothers you.