AFOGLIP M 500 Tablet 15's

INTRODUCTION ABOUT AFOGLIP M 500 TABLET

AFOGLIP M 500 TABLET is used to manage high blood sugar levels in people with type 2 diabetes mellitus. It is a combination of Metformin and Teneligliptin which belongs to the group of medicines called Antidiabetic agents.

Before taking AFOGLIP M 500 TABLET inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have low potassium levels in blood or are severely dehydrated due to excessive vomiting or diarrhea recently. During therapy with AFOGLIP M 500 TABLET, your doctor might regularly monitor blood sugar levels and kidney functions to avoid the risk of unwanted side effects.

AFOGLIP M 500 TABLET is not recommended for use in patients with severe uncontrollable diabetes. It is also not suitable for use in patients with alcoholism and in patients with severe systemic infections. The most common side effects of taking AFOGLIP M 500 TABLET are low blood sugar levels, stomach upset, constipation, flatulence and altered taste sensations. Consult your doctor if any of the above side effects bother you.

USES OF AFOGLIP M 500 TABLET

• Used to manage type II diabetes mellitus

HOW AFOGLIP M 500 TABLET WORKS

AFOGLIP M 500 TABLET contains Metformin and Teneligliptin. Metformin works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body’s sensitivity to insulin. Teneligliptin is a dipeptidyl peptidase-4 inhibitor which works by increasing the release of insulin from pancreas and decreasing the hormones that raise blood sugar levels. This reduces both fasting and post-meal sugar levels. Together, they provide better control of blood sugar.

DIRECTIONS FOR USE

• Take AFOGLIP M 500 TABLET preferably after meals or as advised by your physician
• Swallow the medicine with a glass of water. Do not crush or chew the medicine
• Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition
• Do not stop taking AFOGLIP M 500 TABLET unless your doctor advice you to stop

SIDE EFFECTS OF AFOGLIP M 500 TABLET

Common side effects of AFOGLIP M 500 TABLET:

• hypoglycemia  
• flatulence, diarrhea, constipation, stomach pain, loss of appetite
• changes in taste

Stop taking AFOGLIP M 500 TABLET and consult your doctor immediately if you experience any of the following side effects:

• serious allergic reaction (hives, swelling of the face, lips, tongue or throat causing difficulty in breathing or swallowing)
• severe skin rashes with redness and blistering of the skin
• signs of lactic acidosis (cold hands or feet, dizziness or light-headedness, slow or irregular heartbeat, weakness or tiredness, unusual muscle pain, trouble breathing, sleepiness or drowsiness, stomach pains, nausea or vomiting)
• signs of liver damage (tiredness, loss of appetite, weight loss, with or without yellowing of the skin or whites of the eyes)

WARNING & PRECAUTIONS

PREGNANCY

Monitoring required

AFOGLIP M 500 TABLET should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Safe use of the medicine during pregnancy has not been established.

BREASTFEEDING

Contraindicated

AFOGLIP M 500 TABLET is not recommended for use in breastfeeding mother.

DRIVING AND USING MACHINES

Use with Caution

Do not drive or operate any machines if you feel dizzy after taking AFOGLIP M 500 TABLET.

ALCOHOL

Consult your doctor

Avoid consumption of alcohol while taking AFOGLIP M 500 TABLET as it may increase the risk of unwanted side effects.

KIDNEY

Contraindicated

AFOGLIP M 500 TABLET is not recommended for use in patients with severely reduced kidney functions.

LIVER

Consult your doctor

AFOGLIP M 500 TABLET is not recommended for use in patients with severe liver problems. It should be used with caution in patients with gall stones.

ALLERGY

Contraindicated

Do not take AFOGLIP M 500 TABLET if you are allergic to Metformin or Teneligliptin or any other ingredients of this medicine.

LUNGS

Contraindicated

AFOGLIP M 500 TABLET is not recommended for use in patients with severe infections of the lungs or respiratory tract.

HEART DISEASE

Contraindicated

AFOGLIP M 500 TABLET is not recommended for use in patients with severe heart problems (such as acute heart failure, recent heart attack, arrythmia, prolonged QT interval).

USE IN PEDIATRICS

Consult your doctor

The safety and effectiveness of AFOGLIP M 500 TABLET have not been established in infants, children and adolescents (aged below 18 years).

USE IN GERIATRICS

Consult your doctor

The safety and effectiveness of AFOGLIP M 500 TABLET have not been established in elderly patients (aged 65 years or above).

INTERACTIONS

A. Drug-Drug interactions:

Before taking AFOGLIP M 500 TABLET, inform your doctor if you are taking any of the following medicines such as:

• Anti-diabetics (Ex. glimepiride, glyburide, gliclazide, rosiglitazone, pioglitazone)
• iodine contrast medium (used during X-rays)
• Bronchodilators (Ex. salbutamol or terbutaline)
• Corticosteroids (Ex. hydrocortisone, prednisolone)
• diuretics (Ex. furosemide, hydrochlorothiazide)
• Non-steroidal anti-inflammatory agents (Ex. ibuprofen and celecoxib)
• Antihypertensives (such as atenolol, propranolol, captopril, enalapril, ramipril, lisinopril, losartan, valsartan, olmesartan, telmisartan)
• H2 blockers (Ex. cimetidine)
• Anti-viral agents (Ex. dolutegravir)
• Calcium-channel blockers (Ex. verapamil)
• Antimicrobial (Ex. rifampicin)
• Anti-anginals (Ex. ranolazine)
• Antibiotics (Ex. trimethoprim)
• Anti-cancer agents (Ex. vandetanib, crizotinib and Olaparib)
• Anti-fungal (Ex. isavuconazole)
• Keratolytic agents (Ex. salicylic acid)
• Antidepressants (Ex. phenelzine, selegiline)
• Sympathomimetic agents (Ex. adrenaline)
• Thyroid hormones (Ex. levothyroxine, liothyronine)
• Cardiac glycosides (Ex. quinidine, procainamide, amiodarone, sotalol)

Overdosage:

If you or anyone else accidentally took more of  AFOGLIP M 500 TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are feeling cold, severe nausea or vomiting, stomach pain, unexplained weight loss, muscular cramps and fast breathing.

SYNOPSIS

MORE INFORMATION

Disease Description

Diabetes mellitus (DM) is a chronic metabolic disorder characterized by persistent hyperglycemia. It may be due to impaired insulin secretion, resistance to peripheral actions of insulin, or both. The symptoms of diabetes mellitus are related to high blood glucose levels. They include excessive urination, thirst and hunger, weight loss, increased susceptibility to infections, especially yeast or fungal infections.

FAQs ABOUT AFOGLIP M 500 TABLET