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ANJANI MEDICAL

AF-50

AF-50

Rs. 26.60
Rs. 26.60 Rs. 26.60
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INTRODUCTION ABOUT AF 50MG TABLET

AF 50MG TABLET contains Fluconazole which belongs to the group of medicines called Anti-fungal agents. It is used to manage various fungal infections such as systemic candidiasis (fungal infection affecting the blood, brain, heart, eyes or other parts of the body), mucosal candidiasis (fungal infection affecting the mouth, throat or denture sore mouth), cryptococcosis (fungal infection mainly affecting the lungs and brain), vaginal candidiasis (fungal infection of the vagina and tissues at the opening of vagina (vulva)).      

Also, it manages fungal infections in immunocompromised patients considered at risk as a consequence of HIV infection or low white blood cell count after cytotoxic chemotherapy, radiotherapy or bone marrow transplant.  

Before taking AF 50MG TABLET, inform your doctor if you have liver, kidney or heart problems, abnormal levels of potassium, calcium, or magnesium in your blood, are prone to develop severe skin reactions and have a history of adrenal insufficiency.  

AF 50MG TABLET is not recommended for use in pregnant and breast-feeding women unless clearly advised by the doctor. AF 50MG TABLET should be used with caution in children and adolescents (from birth to 17 years of age). It should be used with caution in elderly patients particularly with renal impairment.

The most common side effects of taking AF 50MG TABLET are headache, nausea, vomiting diarrhea, abdominal pain, and indigestion. Consult your doctor if any of the side effect gets worse.


USES OF AF 50MG TABLET

  • Manage various fungal infections (such as systemic candidiasis, mucosal candidiasis, cryptococcosis and vaginal candidiasis)  
  • Prevents fungal infection in immunocompromised patients

HOW AF 50MG TABLET WORKS

AF 50MG TABLET works by stopping the action of an enzyme called ergosterol, which is an integral part of the fungal cell membrane to increase its cellular permeability. Thereby, making the cell membrane more permeable and stops the fungal growth. This type of action is useful in managing and managing various fungal infections.


DIRECTIONS FOR USE

For Tablet, Capsule: Swallow AF 50MG TABLET with a glass of water. Do not crush or chew the medicine.

For Dispersible Tablet: Disperse AF 50MG TABLET in the specified quantity of water as mentioned in the label. Consume the mixture immediately after reconstitution.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Continue to take AF 50MG TABLET for the stipulated duration prescribed by your doctor to achieve better results.


SIDE EFFECTS OF AF 50MG TABLET

COMMON

  • headache
  • nausea, vomiting
  • diarrhea
  • abdominal pain
  • indigestion
  • acne

UNCOMMON

  • seizures, dizziness, altered nerve sensation and taste
  • skin rash with itching, abnormal odor from skin and dry skin
  • abnormal changes in vision
  • constipation, flatulence and dry mouth
  • thirst, tiredness, body pain and fever
  • weakness, general feeling of discomfort, rigor
  • pharyngitis, herpes simplex viral infection
  • loss of appetite
  • back, muscle pain, muscle spasm
  • renal pain
  • head spinning sensation (vertigo)
  • insomnia, and nervousness
  • muscle overactivity (hypertonia)
  • increased urine output
  • abnormal or heavy vaginal bleeding, painful menses, vaginal discharge and disorder, uterine spasm, female sexual dysfunction  
  • hot flushes, excess sleepiness
  • deafness, increased blood pressure, low oxygen levels, intolerance to oral intake, inflamed and sore mouth (in children)

RARE

  • allergic reactions
  • low white blood cells and platelet count  
  • hair loss
  • damage to liver causing liver failure, hepatitis, and necrosis
  • skin reactions (like steven johnson syndrome and toxic epidermal necrolysis)
  • shaking
  • change in heart rate or rhythm

Stop taking AF 50MG TABLET and contact your doctor immediately if you experience any of the following side effects:

  • sudden wheezing, difficulty in breathing or tightness in the chest, swelling of eyelids, face or lips, itching all over the body, reddening of the skin or itchy red spots
  • skin rash that causes blistering in mouth and tongue
  • signs of liver problems (tiredness, loss of appetite, vomiting and yellowing of the skin or whites of the eyes)
  • signs of DRESS syndrome or drug hypersensitivity syndrome (widespread rash, high body temperature and enlarged lymph nodes)


HOW TO MANAGE SIDE EFFECTS

Diarrhea

Drink lot of fluids, such as water or fruit juice to keep yourself hydrated. Do not take any medicine on your own to manage diarrhea without consulting your doctor.

Dizziness Or Drowsiness

Lie down until dizziness is gone, then get up slowly. Move slowly and carefully, do not hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, alcohol, and drugs. Consult your doctor if the symptom gets worse.

Headache

Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to be relaxed and stress free. Apply pain relieving balm on your forehead if necessary. Consult your doctor if the symptom does not improve.

Nausea And Vomiting

Stick to simple meals while receiving this medicine. Avoid eating oily rich, fried or spicy foods. Do not lie down or sleep immediately after eating. Consult your doctor if the symptom does not improve.

Stomach Pain

Try to take rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. If the symptom does not improve, contact your doctor.


WARNING & PRECAUTIONS

PREGNANCY

Monitoring required

AF 50MG TABLET is not recommended for use during pregnancy unless considered clearly necessary. Consult your doctor before taking AF 50MG TABLET.

BREASTFEEDING

Consult your doctor

AF 50MG TABLET is not recommended for use in breastfeeding women after repeated use or after high dose of this medicine. You may continue breast-feeding after single dose of AF 50MG TABLET. Consult your doctor before taking AF 50MG TABLET.

DRIVING AND USING MACHINES

Use with Caution

Do not drive or operate any machines if you experience dizziness or fits after taking AF 50MG TABLET.

KIDNEY

Use with Caution

AF 50MG TABLET should be used with caution in patients with kidney dysfunction. Consult your doctor before taking AF 50MG TABLET.

LIVER

Use with Caution

AF 50MG TABLET should be used with caution in patients with liver dysfunction. Consult your doctor before taking AF 50MG TABLET.

ALLERGY

Contraindicated

AF 50MG TABLET is not recommended for use if you are allergic to fluconazole or other azole anti-fungals (such as itraconazole or posaconazole)

HEART DISEASE

Use with Caution

AF 50MG TABLET should be used with caution in patients with heart rhythm problems. Consult your doctor for advice before taking AF 50MG TABLET.

USE IN PEDIATRICS

Use with Caution

AF 50MG TABLET should be used with caution in children and adolescents (from birth to 17 years of age). Consult child’s doctor for advice before administration of AF 50MG TABLET to your child.

USE IN GERIATRICS

Use with Caution

AF 50MG TABLET should be used with caution in elderly patients particularly with renal impairment. Your doctor may adjust the dose depending upon kidney function. Consult your doctor for advice before taking AF 50MG TABLET.

OTHERS

AF 50MG TABLET is not recommended for use if you:

  • rare hereditary problems of galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption

Before taking AF 50MG TABLET, inform your doctor if you:

  • have abnormal levels of potassium, calcium, or magnesium in your blood
  • are prone to develop severe skin reactions (itching, reddening of the skin or difficulty in breathing)
  • have history of adrenal insufficiency
  • have no improvement in fungal infection


INTERACTIONS

A. Drug-Drug Interactions:

Before taking AF 50MG TABLET, inform your doctor, if you are taking any of the following medicines:

  • medicines used to manage diabetes medicines (Ex. glyburide, tolbutamide, glipizide, chlorpropamide)
  • medicines used to manage high blood pressure (Ex. hydrochlorothiazide, nifedipine, isradipine, amlodipine, felodipine and losartan)
  • medicines used as blood thinners (Ex. warfarin)
  • medicines used to use to manage rejection of organ transplants (Ex. cyclosporine, tacrolimus, sirolimus)
  • rifampicin or rifabutin (used to manage tuberculosis)
  • astemizole, terfenadine (used to manage certain type of allergies)
  • medicines used to control seizures /fits (Ex. phenytoin or carbamazepine)
  • theophylline (used to control asthma)
  • cisapride (used to manage heartburn)
  • medicines used to manage heart diseases (Ex. quinidine, amiodarone)
  • medicines used to manage depression (Ex. amitriptyline, nortriptyline)
  • pimozide (used to control motor or verbal tics)
  • amphotericin B, voriconazole (medicine for managing various fungal infections)
  • erythromycin (used for managing bacterial infections)
  • cyclosphosphamide, medicines used for management of cancer (Ex. vincristine or vinblastine)
  • alfentanil, fentanyl (used as general anesthetic)
  • halofantrine (for managing malaria)
  • medicines used to manage high cholesterol levels (Ex. atorvastatin, simvastatin, and fluvastatin)
  • medicines used to manage painful conditions with inflammation (Ex. celecoxib, ibuprofen, and naproxen)
  • prednisone (used to manage inflammatory disorders)
  • antiviral medications used to manage HIV infection (Ex.  saquinavir, zidovudine)
  • tofacitinib (used to manage rheumatoid arthritis)
  • ivacaftor (medicine used for managing cystic fibrosis)
  • ibrutinib (used for managing blood cancer)
  • midazolam, triazolam or similar medicines (used to induce sleep and manages anxiety)
  • olaparib (used for managing ovarian cancer)
  • methadone (used to manage chronic pain and also opioid dependance)

Overdosage:

If you or anyone else accidentally takes too much of AF 50MG TABLET, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms of AF 50MG TABLET are hearing, seeing, feeling and thinking things that are not real (hallucination and paranoid behaviour).


SYNOPSIS

Drug :   Fluconazole
Pharmacological Category :   Triazoles
Therapeutic Indication :   Prevent and manages various fungal infections
Dosage Forms :   Tablet, Dispersible tablet, Capsule, Injection, Infusion, Dry syrup, Dusting powder, Gel, Cream, Ear drops, Eye drops, Soap

MORE INFORMATION

  • Keep AF 50MG TABLET out of reach of children
  • Store at room temperature

FAQs ABOUT AF 50MG TABLET

Q: How does AF 50MG TABLET work?

A: AF 50MG TABLET works by stopping the action of an enzyme called ergosterol, which is an integral part of the fungal cell membrane to increase its cellular permeability. Thereby, making the cell membrane more permeable and stops the fungal growth. This type of action is useful in managing and managing various fungal infections.

Q: What if I forget to take a dose of AF 50MG TABLET?

A: If you have missed a dose of AF 50MG TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose. Do not double the dose of AF 50MG TABLET to make up for the missed one as this may increase the chances of developing side effects.

Q: What are the common side effects of AF 50MG TABLET?

A: The common side effects of taking AF 50MG TABLET are headache, nausea, vomiting, diarrhea, abdominal pain, indigestion and acne. Consult your doctor if any of the symptom gets worse or does not improve over the time

Q: Can AF 50MG TABLET be used in elderly patients?

A: AF 50MG TABLET should be used with caution in elderly patients particularly with renal impairment. Your doctor may adjust the dose depending upon kidney function. Consult your doctor for advice before taking AF 50MG TABLET.

Q: Is AF 50MG TABLET safe to use during pregnancy?

A: AF 50MG TABLET is not recommended for use during pregnancy unless clearly advised by the doctor. Consult your doctor before taking AF 50MG TABLET if you are pregnant or planning to get pregnant.

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