ANJANI MEDICAL
GLIMIPREX MF 1/500 Tablet 15's
GLIMIPREX MF 1/500 Tablet 15's
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INTRODUCTION ABOUT GLIMIPREX MF 1/500 TABLET
GLIMIPREX MF 1/500 TABLET is used to manage type 2 diabetes mellitus when diet, exercise and the single agent does not result in adequate glycemic control. It is a combination of Glimepiride and Metformin which belongs to a group of medicines called Antidiabetic agents. Glimepiride lowers blood sugar by causing the pancreas to produce more insulin and helps the body to use insulin efficiently. Metformin reduces the total amount of sugar released into the blood by the liver.
Along management with GLIMIPREX MF 1/500 TABLET follow regular exercise and diet plan as advised by your doctor to achieve better results. Before taking GLIMIPREX MF 1/500 TABLET inform your doctor if you have type 1 diabetes mellitus, diabetic ketoacidosis, severe liver or kidney disease, acute heart problems. Inform your doctor if you are pregnant or breastfeeding. It is not suitable for use in children and adolescents under 18 years of age.
Avoid consumption of alcohol during management with GLIMIPREX MF 1/500 TABLET as it may increase or decrease the blood sugar lowering action of GLIMIPREX MF 1/500 TABLET and increases the risk of lactic acidosis. The most common side effects of taking GLIMIPREX MF 1/500 TABLET are taste disturbance, diarrhea or stomach ache. Contact your doctor if any of the symptoms worsen.
USES OF GLIMIPREX MF 1/500 TABLET
- Used to manage type 2 diabetes mellitus (when diet, exercise and the single agent does not result in adequate glycemic control)
HOW GLIMIPREX MF 1/500 TABLET WORKS
GLIMIPREX MF 1/500 TABLET controls blood glucose levels, where Glimepiride works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin works by lowering glucose production in the liver, delaying glucose absorption from intestine, and increasing the body's sensitivity to insulin.
DIRECTIONS FOR USE
- Take GLIMIPREX MF 1/500 TABLET as advised by your physician
- Swallow GLIMIPREX MF 1/500 TABLET with a glass of water. Do not crush or chew the medicine
- Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition
- Do not stop taking GLIMIPREX MF 1/500 TABLET without informing your doctor.
SIDE EFFECTS OF GLIMIPREX MF 1/500 TABLET
Common side effects of GLIMIPREX MF 1/500 TABLET:
- taste disturbance
- diarrhea
- stomach pain
- loss of appetite
Stop taking GLIMIPREX MF 1/500 TABLET and contact your doctor immediately if you experience any of the following side effects:
- lactic acidosis
- inflammation of the liver which may result in jaundice (yellowing of skin or eyes)
- severe allergic reactions (such as skin rash, hives, and increased sensitivity to sun, inflammation of blood vessels which may develop into serious reactions with difficulty in breathing, fall in blood pressure and sometimes progressing to shock)
- severe low blood sugar levels
WARNING & PRECAUTIONS
PREGNANCY
ContraindicatedGLIMIPREX MF 1/500 TABLET should not be taken during pregnancy. Consult your doctor before taking GLIMIPREX MF 1/500 TABLET if you are planning to become pregnant.
BREASTFEEDING
ContraindicatedGLIMIPREX MF 1/500 TABLET should not be taken during breastfeeding as it may pass through breast milk.
DRIVING AND USING MACHINES
Use with CautionDo not drive or handle any machines if you experience low or high blood sugar levels (symptoms include dizziness, tiredness, shaking or trembling) or if you develop visual problems due to altered blood sugar levels.
ALCOHOL
Consult your doctorAvoid consumption of alcohol during management with GLIMIPREX MF 1/500 TABLET as it may increase or decrease the blood sugar lowering action of GLIMIPREX MF 1/500 TABLET and increases the risk of lactic acidosis.
KIDNEY
Consult your doctorGLIMIPREX MF 1/500 TABLET is not recommended for use in patients with severe kidney disease and it should be used with caution in patients with kidney disease and your dose will be adjusted if needed depending upon kidney function.
LIVER
Consult your doctorGLIMIPREX MF 1/500 TABLET is not recommended if you have severe liver disease and it should be used with caution in patients with liver disease and your dose will be adjusted if needed depending upon liver function.
ALLERGY
ContraindicatedDo not take GLIMIPREX MF 1/500 TABLET if you are allergic (hypersensitive) to Glimepiride or Metformin or other sulfonylureas (such as glipizide, glibenclamide) or sulfonamides (such as sulfamethoxazole).
HEART DISEASE
ContraindicatedGLIMIPREX MF 1/500 TABLET is not recommended for use in patients with acute heart problems or recently had a heart attack or have severe circulatory problems or breathing difficulties (signs of heart failure).
USE IN PEDIATRICS
ContraindicatedGLIMIPREX MF 1/500 TABLET is not recommended for use in children and adolescents (under 18 years of age).
USE IN GERIATRICS
Consult your doctorGLIMIPREX MF 1/500 TABLET is not recommended for use in elderly patients (aged 75 years or above) and it should be used with caution in elderly patients (aged 65 years or above), especially in patients with impaired kidney function. Your doctor may assess your kidney function more frequently during management with GLIMIPREX MF 1/500 TABLET.
OTHERS
GLIMIPREX MF 1/500 TABLET is not recommended for use, if you have:
- type 1 diabetes mellitus
- diabetic ketoacidosis
- uncontrolled diabetes or ketoacidosis
- dehydration
- severe infection
Before taking GLIMIPREX MF 1/500 TABLET inform your doctor if you:
- are recovering from injury, operation, infections with fever, or from other forms of stress
- have glucose-6-phosphate dehydrogenase (G6PD) deficiency
- have various factors which could increase the risk of low blood sugar levels (such as undernourishment, irregular mealtime, missed or delayed meal or period of fasting, change in diet, hormone-induced disorders)
INTERACTIONS
A. Drug-Drug interactions:
Before taking GLIMIPREX MF 1/500 TABLET inform to your doctor, if you are taking any of these medicines:
- Sulphonylureas (Ex. glibenclamide, insulin)
- Anabolics
- Anticoagulants (Ex. Warfarin)
- Anticonvulsants (Ex. Fenfluramine, Phenytoin)
- NSAIDs (Ex. Phenylbutazone, azopropazone, oxyphenbutazone)
- Class 1a anti-arrhythmic agent (Ex. Disopyramide)
- Fibrates (Ex. fenofibrate, nicotinic acid, colesevelam)
- Angiotensin-converting enzyme (Ex. captopril, lisinopril)
- Diuretics (Ex. furosemide, chlorthalidone, hydrochlorothiazide or diazoxide)
- Monoamine oxidase inhibitors (Ex. isocarboxazid, selegiline and chlorpromazine)
- Antigout agents (Ex. Allopurinol, probenecid, sulfinpyrazone)
- Alkylating agents (Ex. Cyclophosphamide, ifosfamide, trofosfamide)
- Tetracyclines (Ex. minocycline, doxycycline, chloramphenicol, fluconazole, miconazole
- Quinolones (Ex. moxifloxacin, ciprofloxacin, clarithromycin, rifampicin
- Tritoqualine, glucocorticoids (Ex. beclomethasone, hydrocortisone)
- Hemorrheologic agents (Ex. Pentoxifylline)
- Sulfonamides (Ex. sulfamethoxazole)
- Androstane class (Ex. testosterone)
- Natural or synthetic (Ex. oestrogens, progestogens)
- Sympatholytics (Ex. clonidine, methyldopa)
- Hormones (Ex. Levothyroxine)
- Adrenaline and sympathomimetics (Ex. phenylephrine, norepinephrine)
- Laxatives (Ex. bisacodyl)
- Antidiabetics (Ex. Glucagon)
- Barbiturates (Ex. pentobarbital, amobarbital)
- Carbonic anhydrase inhibitors (Ex. Acetazolamide)
Overdosage:
If you or anyone else takes too much of GLIMIPREX MF 1/500 TABLET, contact your doctor immediately or go to a nearest hospital straight away. Overdosage symptoms of GLIMIPREX MF 1/500 TABLET includes risk of low blood sugar levels. Symptoms of lactic acidosis include vomiting, bellyache with muscle cramps, general feeling of not being well with severe tiredness, reduced body temperature, low heartbeat, and difficulty in breathing.
SYNOPSIS
| Drug | : | Glimepiride, Metformin |
| Pharmacological Category | : | Sulfonylureas, Biguanides |
| Therapeutic Indication | : | Type II diabetes mellitus |
| Dosage Forms | : | Tablet |
MORE INFORMATION
FAQs ABOUT GLIMIPREX MF 1/500 TABLET
Q: What is GLIMIPREX MF 1/500 TABLET used for?
A: GLIMIPREX MF 1/500 TABLET is used to manage type 2 diabetes mellitus in adults. This combination helps regulate blood sugar levels effectively in individuals whose blood sugar is not adequately controlled by diet, exercise, or a single diabetes medication. It helps reduce the risk of diabetes-related complications such as heart disease, nerve damage, or kidney issues.
Q: How GLIMIPREX MF 1/500 TABLET works?
A: GLIMIPREX MF 1/500 TABLET contains a combination of two medicines namely, glimepiride and metformin. Glimepiride stimulates the pancreas to release more insulin, a hormone that lowers blood sugar levels. It also improves the body’s response to insulin. Metformin decreases the amount of sugar produced by the liver and reduces sugar absorption in the intestines. It also enhances the body’s ability to use insulin more effectively, making it a comprehensive treatment for blood sugar control.
Q: What is the best time to take GLIMIPREX MF 1/500 TABLET?
A: It is usually recommended to take GLIMIPREX MF 1/500 TABLET with meals to minimize the risk of gastrointestinal side effects such as nausea or upset stomach. Following your doctor’s instructions regarding the timing is essential, as they might tailor the dose to suit your lifestyle and blood sugar patterns.
Q: How many doses of GLIMIPREX MF 1/500 TABLET can be taken in a day?
A: The dosage depends on the individual’s medical condition, blood sugar levels, and response to treatment. Typically, it is taken once or twice daily with meals, but the exact dose should be determined by a doctor. Taking more than the prescribed dose can lead to hypoglycemia (low blood sugar), so it’s crucial to stick to the recommended schedule.
Q: Can GLIMIPREX MF 1/500 TABLET be used during pregnancy?
A: The combination of Glimepiride + Metformin is generally not recommended during pregnancy due to the potential risk of harming the unborn baby. Instead, insulin is preferred for controlling blood sugar levels in pregnant women with diabetes. If you are pregnant or planning to conceive, consult your doctor for a safe treatment plan.
Q: Can GLIMIPREX MF 1/500 TABLET control blood sugar levels?
A: Yes, this medicine is highly effective in controlling blood sugar levels in people with type 2 diabetes especially when diet, lifestyle changes and treatment with single agents does not yield optimum blood sugar control. However, its effectiveness also depends on maintaining a healthy lifestyle, including regular exercise and a balanced diet. Regular monitoring of blood sugar is essential to ensure the medication works optimally.
Q: Who should not use GLIMIPREX MF 1/500 TABLET?
A: GLIMIPREX MF 1/500 TABLET is not suitable for individuals with severe kidney or liver disease, type 1 diabetes or diabetic ketoacidosis, known allergies to glimepiride, metformin, or any other ingredients in the medicine, or a history of lactic acidosis. Therefore, always inform your doctor about any pre-existing conditions or medications you are taking to avoid adverse effects.
Q: What are the common side effects of GLIMIPREX MF 1/500 TABLET?
A: The most common side effects of GLIMIPREX MF 1/500 TABLET include nausea, vomiting, diarrhea, stomach pain, dizziness, or low blood sugar (hypoglycemia. Consult your doctor if any of these side effects worsens.
Q: Is GLIMIPREX MF 1/500 TABLET safe?
A: Yes, GLIMIPREX MF 1/500 TABLET is generally safe when taken as prescribed. However, regular monitoring of kidney and liver function is necessary, as prolonged use can affect these organs. Additionally, following the recommended dose and schedule minimizes the risk of side effects.
Q: Can GLIMIPREX MF 1/500 TABLET be taken on an empty stomach or before food?
A: No, it is best taken with food to reduce the risk of stomach upset and hypoglycemia. Food helps slow down the absorption of glimepiride, preventing a sudden drop in blood sugar levels, which can cause dizziness or weakness.
Q: Is GLIMIPREX MF 1/500 TABLET safe for kidney patients?
A: GLIMIPREX MF 1/500 TABLET is not suitable for individuals with severe kidney disease, as it can increase the risk of lactic acidosis, a potentially life-threatening condition. Mild to moderate kidney impairment requires dose adjustment and close monitoring. Always consult your doctor before starting or continuing this medication.
Q: How long will it take for GLIMIPREX MF 1/500 TABLET to control blood sugar levels?
A: GLIMIPREX MF 1/500 TABLET begins to lower blood sugar within a few hours of taking a dose. However, achieving optimal blood sugar control may take a few weeks, depending on individual response and adherence to the prescribed regimen, diet, and exercise plan.
Q: Can I stop taking GLIMIPREX MF 1/500 TABLET once my blood sugar is controlled?
A: No, stopping the medication without your doctor’s advice can cause your blood sugar levels to rise again, leading to complications. Diabetes is a chronic condition requiring ongoing management. Your doctor may adjust the dose or switch medications based on your progress, but self-discontinuation is not recommended.
