Geminor 2mg Tablet 10'S

INTRODUCTION ABOUT GEMINOR 2MG TABLET

GEMINOR 2MG TABLET is used for the management of Type II diabetes mellitus when diet and exercise alone does not result in adequate blood sugar control. It contains Glimepiride which belongs to the group of medicines called Anti-diabetic agents. It stimulates the pancreas to secrete more insulin (a hormone involved in glucose metabolism). It also makes our body more sensitive to insulin which helps in digesting the circulating sugars (glucose) in the blood, thereby reducing blood sugar levels.

Along with the therapy, your doctor might ask you to make certain lifestyle changes such as following a healthy diet, regular physical exercise and quitting alcohol consumption. Before taking the medicine, inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have any hormonal problems, genetic disorders (such as G6PD deficiency) or if you are malnourished, starved, on an irregular diet. GEMINOR 2MG TABLET is not suitable for use in patients with type I diabetes mellitus. Consult your doctor if you are pregnant or planning to become pregnant or breastfeeding.

The most common side effect of taking GEMINOR 2MG TABLET is hypoglycemia (low blood sugar levels) which can be identified through symptoms such as increased hunger, sweating, shakiness, weakness or an irregular heartbeat. To avoid this, your doctor will periodically monitor your blood sugar levels and adjust the dose of the medicine accordingly. You can also carry a sugary snack (such as biscuits, glucose drinks or sweet candies) along with you as a precaution and have them immediately if you experience any signs of hypoglycemia. However, consult your doctor if there is no improvement in your condition.

USES OF GEMINOR 2MG TABLET

• Used to manage Type II diabetes mellitus

HOW GEMINOR 2MG TABLET WORKS

GEMINOR 2MG TABLET stimulates the pancreas to secrete more insulin (a hormone involved in glucose metabolism). It also makes our body more sensitive to insulin which helps in digesting the circulating sugars (glucose) in the blood, thereby reducing blood sugar levels.

DIRECTIONS FOR USE

• Take GEMINOR 2MG TABLET preferably after meals or as advised by your physician
• Swallow the medicine with a glass of water. Do not crush or chew the medicine.
• Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition
• Do not stop taking GEMINOR 2MG TABLET unless your doctor advice you to stop

SIDE EFFECTS OF GEMINOR 2MG TABLET

Common side effects of GEMINOR 2MG TABLET:

• hypoglycemia (low blood sugar levels)

Stop taking GEMINOR 2MG TABLET and contact your doctor immediately if you experience any of the following side effects:

• severe allergic reaction (inflammation of blood vessels, skin rash, swelling of the face, eyelids, lips, tongue or throat which causes difficulty in breathing or swallowing, drop in blood pressure)
• signs of liver problems (such as fever, yellowing of skin and whites of the eyes, weakness, fatigue, weight loss and loss of appetite)
• increased skin sensitivity to sun
• signs of severe decrease in blood sugar level (such as confusion, headache, excessive sweating, clammy skin, trembling, weakness, double vision, excessive hunger, nausea, vomiting, problems in sleeping, feeling agitated, unable to concentrate, drowsiness, slowed reactions, depression, trouble seeing or speaking, paralysis, numbness, dizziness, hallucinations, difficulty in breathing, slowed or faster heartbeat with chest pain)

WARNING & PRECAUTIONS

PREGNANCY

Monitoring required

There are no adequate and well-controlled studies in pregnant women. GEMINOR 2MG TABLET should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

BREASTFEEDING

Consult your doctor

It is not known whether GEMINOR 2MG TABLET is excreted in human milk. Consult your doctor for advice.

DRIVING AND USING MACHINES

Use with Caution

Do not drive or operate any heavy tools or machines if your ability is affected by the medicine.

ALCOHOL

Consult your doctor

Avoid consumption of alcohol while taking GEMINOR 2MG TABLET as it may increase the risk of unwanted side effects.

KIDNEY

Consult your doctor

GEMINOR 2MG TABLET is not recommended for use in patients with severe kidney problems. It should be used with caution in patients with other kidney problems.

LIVER

Consult your doctor

GEMINOR 2MG TABLET is not recommended for use in patients with severe liver problems. It should be used with caution in patients with other liver problems.

ALLERGY

Contraindicated

Do not take GEMINOR 2MG TABLET if you are allergic to Glimepiride or any other ingredients of this medicine.

USE IN PEDIATRICS

Contraindicated

GEMINOR 2MG TABLET is not recommended in pediatric patients because of its adverse effects on body weight and hypoglycemia.

USE IN GERIATRICS

Use with Caution

GEMINOR 2MG TABLET should be used with caution in elderly patients (aged above 65 years).

INTERACTIONS

A. Drug-Drug interactions:

Before taking GEMINOR 2MG TABLET, inform your doctor if you are taking any of the following medicines:

• Anti-diabetics agents (Ex. insulin or metformin)
• Non-steroidal anti-inflammatory agents (Ex. aspirin, ibuprofen, phenylbutazone, azopropazone, oxyphenbutazone)
• Antibiotics (Ex. amikacin, nitrofurantoin, sulfamethoxazole, tetracyclines, chloramphenicol, ciprofloxacin, clarithromycin)
• Anti-fungal agents (Ex. fluconazole, miconazole)
• Anti-coagulants (Ex. warfarin)
• Class II AASs (Ex. nandrolone, oxymethalone)
• Hormone replacement (Ex. testosterone)
• Benzamides (Ex. moclobemide, isocarboxazid, phenelzine, tranylcypromine, fluoxetine)
• Anti-lipidemic agents (Ex. fenofibrate, nicotinic acid, colesevelam)
• Angiotensin-converting enzyme (ACE) inhibitors (Ex. enalapril, lisinopril, ramipril)
• Antihypertensives (Ex. atenolol, propranolol, telmisartan, olmesartan, clonidine, guanethidine and reserpine)
• Class 1a anti-arrhythmic agent (Ex. disopyramide)
• Anti-gout agents (Ex. allopurinol, probenecid, sulfinpyrazone)
• Alkylating agents (Ex. cyclophosphamide, ifosfamide, trofosfamide)
• Anticonvulsants (Ex. fenfluramine)
• Hemorrheologic agents (Ex. pentoxifylline)
• Enzyme inhibitor (Ex. tritoqualine)
• Alpha blockers (Ex. prazosin, doxazosin)
• Hormonal replacement therapy (Ex. estradiol)
• Thiazide diuretics (Ex. hydrochlorothiazide)
• Hormones (Ex. Levothyroxine)
• Antipsychotics (Ex. chlorpromazine, prochlorperazine, lithium)
• corticosteroids (Ex. prednisolone, betamethasone)
• Bronchodilators (Ex. salbutamol, terbutaline)
• Alpha- and beta-adrenergic agonists (Ex. adrenaline)
• Laxatives (Ex. lactulose, liquid paraffin)
• Anti-convulsant (Ex. phenytoin)
• Barbiturates (Ex. phenobarbital)
• Carbonic anhydrase inhibitors (Ex. azetazolamide)
• Glycogenolytic agents (Ex. Glucagon, diazoxide)
• H2 blockers (Ex. Cimetidine)

Overdosage:

If you or anyone else accidentally took more of GEMINOR 2MG TABLET, you may experience the signs of hypoglycemia (such as increased hunger, sweating, headache, feeling clammy, restless or aggressive, shakiness, fast heartbeat and confusion). To manage this, consume any sugary food immediately. If the symptom did not improve or worsens contact your doctor immediately.

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