ANJANI MEDICAL
Dibizide M Tablet 10'S
Dibizide M Tablet 10'S
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INTRODUCTION ABOUT DIBIZIDE M TABLET
DIBIZIDE M TABLET is a combination of Glipizide and Metformin which belongs to the group of medicines called Antidiabetic agents. It is used in adults to manage type II diabetes mellitus when diet, exercise and management with single agents does not result in adequate sugar control.
Type II diabetes mellitus is a chronic disease characterized by abnormally high levels of glucose in the blood. It is caused due to inadequate production of a hormone called insulin (produced by pancreas to metabolize glucose) in the body or due to inadequate sensitivity of body cells to the actions of insulin.
Before taking DIBIZIDE M TABLET, inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have any hormonal imbalance, alcoholism, or if you are malnourished, starved, on an irregular diet as a precaution.
DIBIZIDE M TABLET is strictly not recommended for use in patients with type I diabetes mellitus, severe heart failure or lactic acidosis. It is also not suitable for use in pregnant or breastfeeding women.
Along with the management, follow the diet and lifestyle changes advised by your doctor to achieve better results. Avoid smoking and consumption of alcohol while taking DIBIZIDE M TABLET as it may aggravate your existing condition.
The most common side effects of taking DIBIZIDE M TABLET are low blood sugar levels, nausea, vomiting, diarrhea, stomach upset and changes in taste. Consult your doctor if any of these side effect worsens.
USES OF DIBIZIDE M TABLET
- Manage type II diabetes mellitus
HOW DIBIZIDE M TABLET WORKS
DIBIZIDE M TABLET stimulates the pancreas to secrete more insulin (a hormone involved in glucose metabolism). It also makes our body more sensitive to insulin which helps in digesting the circulating sugars (glucose) in the blood, thereby reducing blood sugar levels. Additionally, it can also reduce the amount of glucose produced by the liver and reduces its absoprtion in the body.
DIRECTIONS FOR USE
Take DIBIZIDE M TABLET preferably 30 minutes before meals or as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Do not stop taking DIBIZIDE M TABLET unless your doctor advice you to stop.
SIDE EFFECTS OF DIBIZIDE M TABLET
SERIOUS
Stop taking DIBIZIDE M TABLET and contact your doctor immediately if you experience any of the following side effects:
- severe allergic reaction (such as skin rash, swelling of the face, eyelids, lips, tongue, or throat which causes difficulty in breathing or swallowing)
- signs of severe decrease in blood sugar level (such as confusion, headache, excessive sweating, clammy skin, trembling, weakness, double vision, excessive hunger, nausea, vomiting, problems in sleeping, feeling agitated, unable to concentrate, drowsiness, loss of consciousness, slowed reactions, depression, trouble seeing or speaking, paralysis, numbness, dizziness, hallucinations, difficulty in breathing, slowed or faster heartbeat with chest pain)
- signs of liver problems (such as nausea or vomiting, stomach pain, unusual or unexplained tiredness, loss of appetite, dark urine, yellowing of the skin or the whites of the eyes)
- signs of lactic acidosis (cold hands or feet, dizziness or light-headedness, slow or irregular heartbeat, weakness or tiredness, unusual muscle pain, trouble breathing, sleepiness or drowsiness, stomach pains, nausea or vomiting)
COMMON
- hypoglycemia (low blood sugar levels)
- nausea, vomiting
- diarrhea, stomach pain, loss of appetite
- changes in taste, metallic taste
UNCOMMON
- dizziness, drowsiness
- feeling shaky
- blurred vision
- eczema (skin inflammation)
HOW TO MANAGE SIDE EFFECTS
Diarrhea
Hydrate yourself by drinking plenty of fluids, such as water or fruit juices. Consuming ORS can also be beneficial. Do not self-manage diarrhea on your own. Consult your doctor if your diarrhea becomes uncontrollable.
Dizziness Or Drowsiness
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol. Consult your doctor if your dizziness worsens.
Headache
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Hypoglycemia
Have foods rich in sugars such as fruit juices, glucose drinks, candies, honey or biscuits. Check your blood sugar after 10 minutes. If not gained optimum level, take another sugary snack, or a drink and check the blood sugar again. Consult your doctor if there is no improvement in your condition.
Nausea And Vomiting
Take DIBIZIDE M TABLET with or just after meals. Stick to simple meals. Avoid eating oily or spicy foods. Consult your doctor if your nausea worsens.
WARNING & PRECAUTIONS
PREGNANCY
ContraindicatedDIBIZIDE M TABLET is not recommended for use in pregnant women. Therefore, consult your doctor before taking it.
BREASTFEEDING
ContraindicatedDIBIZIDE M TABLET is not recommended for use in breastfeeding women. Therefore, consult your doctor before taking it.
DRIVING AND USING MACHINES
Use with CautionDo not drive or operate any heavy tools or machines if your ability is affected by DIBIZIDE M TABLET.
ALCOHOL
Consult your doctorAvoid consumption of alcohol while taking DIBIZIDE M TABLET as it may increase the risk of unwanted side effects.
KIDNEY
Consult your doctorDIBIZIDE M TABLET is not recommended for use in patients with severe kidney problems. It should be used with caution in patients with other kidney problems. Therefore, consult your doctor before taking it.
LIVER
Consult your doctorDIBIZIDE M TABLET is not recommended for use in patients with severe liver problems. It should be used with caution in patients with other liver problems. Therefore, consult your doctor before taking it.
ALLERGY
ContraindicatedDo not take DIBIZIDE M TABLET if you are allergic to Glipizide, Metformin or to any other sulfonylureas (Ex. glyburide, glimepiride) or sulphonamides (Ex. sulfasalazine).
LUNGS
ContraindicatedDIBIZIDE M TABLET is not recommended for use in patients with breathing problems (such as asthma or COPD) or lung infections. Therefore, consult your doctor before taking it.
HEART DISEASE
Consult your doctorDIBIZIDE M TABLET is not recommended for use in patients with severe heart problems (such as heart failure). It should be used with caution in patients with other heart problems. Therefore, consult your doctor before taking it.
USE IN PEDIATRICS
ContraindicatedDIBIZIDE M TABLET is not recommended for use in children and in adolescents (aged below 18 years). Therefore, consult your doctor before taking it.
USE IN GERIATRICS
Use with CautionDIBIZIDE M TABLET should be used with caution in elderly patients (aged above 65 years). Therefore, consult your doctor before taking it.
OTHERS
DIBIZIDE M TABLET is not recommended for use if you:
- have type I diabetes mellitus (insulin dependent diabetes)
- have lactic acidosis (build-up of lactic acid in the body)
- have diabetic ketoacidosis (a diabetic complication causing episodes of fatigue, nausea, frequent urination and muscular stiffness)
- have uncontrollable diabetes
- are an alcoholic
- are severely dehydrated (due to recent diarrhea or vomiting)
- have any serious infection
- have shock or problems in blood circulation
Before taking DIBIZIDE M TABLET, inform your doctor if you:
- have G6PD deficiency
- are on fating or malnourished, starved, on an irregular diet, or feeling weak
- perform extreme physical exercises without proper carbohydrate intake
- have hormonal problems (Ex. disorders of pituitary gland, adrenal cortex or thyroid gland)
- smoke
- are scheduled for any X-rays or a major surgery
INTERACTIONS
A. Drug-Drug Interactions:
Before taking DIBIZIDE M TABLET, inform your doctor if you are taking any of the following medicines:
- other medicines used to manage diabetes (Ex. teneligliptin, rosiglitazone, pioglitazone, glimepiride)
- diuretics (used to reduce edema and to manage hypertension) Ex. furosemide, hydrochlorothiazide
- medicines used to manage pain and inflammation (such as ibuprofen and celecoxib)
- medicines used to manage high blood pressure (such as atenolol, propranolol, captopril, enalapril, ramipril, lisinopril, losartan, valsartan, olmesartan, telmisartan)
- medicines used to manage asthma (Ex. salbutamol or terbutaline)
- corticosteroids (used to manage pain and inflammation) Ex. hydrocortisone, prednisolone
- verapamil (a medicine used to manage heart problems)
- rifampicin (a medicine used to manage tuberculosis)
- cimetidine (a medicine used to manage stomach ulcer)
- dolutegravir (a medicine used to manage HIV infection)
- ranolazine (a medicine used to manage chest pain)
- trimethoprim (a medicine used to manage bacterial infection)
- vandetanib, crizotinib and olaparib (medicines used to manage cancer)
- antifungal medicines (used to manage fungal infections) such as miconazole, isavuconazole or fluconazole
- antibiotics (used to manage bacterial infections) such as fluorquinolones (Ex. ciprofloxacin, moxifloxacin), clarithromycin, co-trimoxazole, rifampicin, chlormaphenicol, tetracyclines or sulphonamides (Ex. sulphasalazine)
- medicines used to manage stomach ulcers such as ranitidine, famotidine, cimetidine
- medicines used to manage depression (such as moclobemide, isocarboxazid, phenelzine and tranylcypromine)
- medicines used for pain relief (Ex. aspirin, phenylbutazone, ibuprofen, phenylbutazone, azapropazone)
- medicines to manage mental illness (such as chlorpromazine, prochlorperazine, lithium)
- danazol (a medicine used to manage breast disorders, heavy menstrual bleeding and endometriosis)
- medicines used for blood thinning (Ex. warfarin)
- oral contraceptives (birth control pills) Ex. drospirenone, ethinylestradiol
- sulfinpyrazone, probenecid (medicines used to manage gout)
- thyroid hormones such as thyroxine (used to manage thyroid deficiency)
- phenytoin (a medicine used to manage epilepsy)
- clofibrate, nicotinic acid (medicines used to manage high blood cholesterol levels)
- isoniazid (a medicine used to manage tuberculosis)
Overdosage:
If you or anyone else accidentally take too much of DIBIZIDE M TABLET, you may experience the signs of hypoglycemia (such as increased hunger, sweating, headache, feeling clammy, restless or aggressive, shakiness, fast heartbeat and confusion). To manage this, consume any sugary food immediately. If the symptom did not improve or worsens consult your doctor immediately. Other symptoms of overdosage might include vomiting, stomach pain with muscle cramps, feeling generally unwell with severe tiredness and difficulty in breathing.
SYNOPSIS
| Drug | : | Glipizide, Metformin |
| Pharmacological Category | : | Sulfonylureas, Biguanides |
| Therapeutic Indication | : | Type II diabetes mellitus |
| Dosage Forms | : | Tablet |
MORE INFORMATION
- Keep DIBIZIDE M TABLET out of reach of children
- Store DIBIZIDE M TABLET at room temperature
FAQs ABOUT DIBIZIDE M TABLET
Q: What is DIBIZIDE M TABLET used for?
A: DIBIZIDE M TABLET is an antidiabetic medicine used to manage type II diabetes mellitus when diet, exercise and management with single agents does not result in adequate response.
Q: How and when to take DIBIZIDE M TABLET?
A: Take DIBIZIDE M TABLET preferably 30 minutes before meals or as advised by your physician. Swallow the medicine with a glass of water. Do not cursh or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Q: How long should I take DIBIZIDE M TABLET?
A: You need to take DIBIZIDE M TABLET as long as your doctor prescribes you the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Q: What is the best time to take DIBIZIDE M TABLET?
A: DIBIZIDE M TABLET must be taken just before meals to avoid gastrointestinal side effects.
Q: What to do if I forgot to take a dose of DIBIZIDE M TABLET?
A: If you forgot to take a dose of DIBIZIDE M TABLET, take it as soon as you remember. However, if it is time for the next dose of DIBIZIDE M TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of DIBIZIDE M TABLET to compensate the missed ones.
Q: Can I stop taking DIBIZIDE M TABLET without consulting your doctor?
A: No. You should not stop taking DIBIZIDE M TABLET without consulting your doctor because it may lead to reversal of symptoms. If you feel better after using DIBIZIDE M TABLET, consult your doctor for advice.
Q: Will taking a higher dose of DIBIZIDE M TABLET be more effective?
A: No, taking a higher dose of DIBIZIDE M TABLET will not be effective rather it can lead to toxicity. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.
Q: Can I take medication for high blood pressure along with DIBIZIDE M TABLET?
A: It is not advisable to take medicines to control blood pressure while taking DIBIZIDE M TABLET without consulting your doctor, as they have known interactions with DIBIZIDE M TABLET.
Q: How to manage the side effects of DIBIZIDE M TABLET?
A: Low blood sugar is a common side effect of taking DIBIZIDE M TABLET. Try to have sugar rich food items such as fruit juice, glucose tablets or gel, soft drinks, honey or sugary candy. Check your blood sugar after 10 minutes. If not gained optimum level, take another sugary snack, or drink, and check the blood sugar levels once again. If your condition did not improve, consult your doctor immediately.
Q: Can DIBIZIDE M TABLET be taken with insulin?
A: Co-administration of DIBIZIDE M TABLET with insulin is considered risky as they can increase the chances of hypoglycemia (low blood sugar levels). Therefore, consult your doctor before taking it.
Q: Can DIBIZIDE M TABLET be used in pregnant women?
A: DIBIZIDE M TABLET is not recommended for use in pregnant women. Therefore, consult your doctor for advice before taking it.
Q: What are the side effects of taking DIBIZIDE M TABLET?
A: The most common side effects of taking DIBIZIDE M TABLET are low blood sugar levels, nausea, vomiting, diarrhea, stomach upset and changes in taste. Consult your doctor if any of these side effect worsens.
Q: Can DIBIZIDE M TABLET cause dizziness?
A: Yes. Dizziness is a common side effect of using DIBIZIDE M TABLET. In case you experience dizziness, lie down until it passes, then get up slowly and carefully. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, and alcohol. Do not drive or use machinery to avoid accidents. Consult your doctor if you experience dizziness continuously for a long time after taking DIBIZIDE M TABLET.
Q: What precautions do I need to follow while taking DIBIZIDE M TABLET?
A: Before taking DIBIZIDE M TABLET inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have any severe systemic infections or are severely dehydrated due to excessive vomiting or diarrhea recently. Along with the therapy, follow the diet and lifestyle changes advised by your doctor to achieve better results. Consult your doctor before taking DIBIZIDE M TABLET if you are pregnant or breastfeeding.
